Many people believe that hairless breeds, such as the Sphynx, or the Siberian cat are hypoallergenic.  No breed is actually hypoallergenic.  People are most commonly allergic to the Fel d 1 protein which is found in cat saliva (90% of the population, but you may one of the few allergic to a different cat protein).  As all cats make saliva, all cats can cause an allergic reaction.  There are a few breeders who claim to breed for cats who do not produce Fel d 1, but unless the breeder has proof to have genetically-engineered a Fel d 1 knockout cat, then it is unlikely to be true.  No cat breed exists which does not produce the Fel d 1 protein at this time.  Individual cats may produce a low amount of the Fel d 1 protein.  As a rescue, we do not have the resources to genetically test each of our cats for the absence of the gene and do not claim that any of our rescue cats are hypoallergenic.